Article
Evolution of Boolean networks under selection for a robust response to external inputs yields an extensive neutral space.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Feb 2010
Szejka Agnes, Drossel Barbara
Abstract excerpt
We study the evolution of Boolean networks as model systems for gene regulation. Inspired by biological networks, we select simultaneously for robust attractors and for the ability to respond to external inputs by changing the attractor. Mutations change the connections between the nodes and the update functions. In order to investigate the influence of the type of update functions, we perform our simulations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
