The effect of mutational robustness on the evolvability of multicellular organisms and eukaryotic cells.

Abstract excerpt

Canalization involves mutational robustness, the lack of phenotypic change as a result of genetic mutations. Given the large divergence in phenotype across species, understanding the relationship between high robustness and evolvability has been of interest to both theorists and experimentalists. Although canalization was originally proposed in the context of multicellular organisms, the effect of...

Topics

• Evolution, Molecular
• Eukaryotic Cells
• Models, Genetic
• Mutation
• Phenotype