Robustness, evolvability, and the logic of genetic regulation.

Abstract excerpt

In gene regulatory circuits, the expression of individual genes is commonly modulated by a set of regulating gene products, which bind to a gene's cis-regulatory region. This region encodes an input-output function, referred to as signal-integration logic, that maps a specific combination of regulatory signals (inputs) to a particular expression state (output) of a gene. The space of all possible...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computer Simulation
• Share to Evolution, Molecular
• Share to Gene Regulatory Networks