Article
Why and how genetic canalization evolves in gene regulatory networks.
BMC evolutionary biology - 8 Nov 2016
Rünneburger Estelle, Le Rouzic Arnaud
Abstract excerpt
BACKGROUND: Genetic canalization reflects the capacity of an organism's phenotype to remain unchanged in spite of mutations. As selection on genetic canalization is weak and indirect, whether or not genetic canalization can reasonably evolve in complex genetic architectures is still an open question. In this paper, we use a quantitative model of gene regulatory network to describe the conditions in which...
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