Article
Association between CDKN1A Ser31Arg and C20T gene polymorphisms and colorectal cancer risk and prognosis.
In vivo (Athens, Greece) - 1 Jan 2000
Cacina Canan, Yaylim-Eraltan Ilhan, Arikan Soykan, Saglam Esra Kaytan, Zeybek Umit, Isbir Turgay
Abstract excerpt
BACKGROUND: CDKN1A (p21(WAF1/CIP1)) plays an important role in cell cycle regulation. Somatic alterations in genes which regulate cell division have been shown to be related to different types of cancer prognosis and survival. The purpose of this study was to investigate the effect of the CDKN1A Ser31Arg and C20T gene polymorphisms in Turkish patients with colorectal cancer. PATIENTS AND METHODS: CDKN1A Ser/Arg...
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