Article
Association between CDKN1A gene rs1801270 polymorphisms and susceptibility to colorectal cancser in an Iranian population.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2023
Zali Neda, Savabkar Sanaz, Tajali Raziye, Chaleshi Vahid, Nazemalhosseini Mojarad Ehsan, Vahedi Mohsen, Hashemi Mehrdad, Asadzadeh Aghdaei Hamid
Abstract excerpt
CDKN1A gene is implicated in cell differentiation, development process, repair, apoptosis, senescence, migration, and tumorigenesis. Somatic alterations and polymorphisms may interfere in the function of CDKN1A, and this could affect the individual susceptibility to colorectal cancer (CRC). Here in, we evaluated the importance of single nucleotide polymorphic variants in codon 31 of CDKN1A (rs1801270: C > A) for...
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