Article
Atrophy and dysfunction of parahippocampal white matter in mild Alzheimer's disease.
Neurobiology of aging - 1 Jan 2012
Wang Changsheng, Stebbins Glenn T, Medina David A, Shah Raj C, Bammer Roland, Moseley Michael E, deToledo-Morrell Leyla
Abstract excerpt
In addition to atrophy of mesial temporal lobe structures critical for memory function, white matter projections to the hippocampus may be compromised in individuals with mild Alzheimer's disease (AD), thereby compounding the memory difficulty. In the present study, high-resolution structural imaging and diffusion tensor imaging techniques were used to examine microstructural alterations in the parahippocampal...
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