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Article

Functional alterations in memory networks in early Alzheimer's disease.

Neuromolecular medicine - 1 Mar 2010

Sperling Reisa A, Dickerson Bradford C, Pihlajamaki Maija, Vannini Patrizia, LaViolette Peter S, Vitolo Ottavio V, Hedden Trey, Becker J Alex, Rentz Dorene M, Selkoe Dennis J, Johnson Keith A

Abstract excerpt

The hallmark clinical symptom of early Alzheimer's disease (AD) is episodic memory impairment. Recent functional imaging studies suggest that memory function is subserved by a set of distributed networks, which include both the medial temporal lobe (MTL) system and the set of cortical regions collectively referred to as the default network. Specific regions of the default network, in particular, the posteromedial...

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Identifiers

PMID: 20069392
DOI: 10.1007/s12017-009-8109-7
PMCID: PMC3036844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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