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Article

Identification of key genes for carcinogenic pathways associated with colorectal adenoma-to-carcinoma progression

20 Jan 2010

Abstract excerpt

Colorectal adenomas form a biologically and clinically distinct intermediate stage in development of colorectal cancer (CRC) from normal colon epithelium. Only 5% of adenomas progress into adenocarcinomas, indicating that malignant transformation requires other biological alterations than those involved in adenoma formation. The present study aimed to explore which cancer-related biological processes are affected...

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PMID: 20358421
DOI: 10.1007/s13277-009-0012-1

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