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Sex Difference of Colon Adenoma Pathway and Colorectal Carcinogenesis

31 Aug 2023

Abstract excerpt

Colorectal cancer (CRC) is one of the most common causes of cancer morbidity in both sexes but shows sex differences. First, sex-specific differences in tumor recurrence and survival rates have been reported. For example, the development of CRC is found about 1.5 times higher and 4-8 years earlier in males compared to females, suggesting the protective role of estrogen in the disease. Furthermore, female patients...

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PMID: 37652658
DOI: 10.5534/wjmh.230085

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