Article
P38 expression in colorectal adenomas: relationships to cell proliferation, stem phenotype and AKT pathway proteins.
Minerva gastroenterologica e dietologica - 1 Sept 2020
Handra-Luca Adriana, Bendib Mouna, Magkou Christina
Abstract excerpt
BACKGROUND: The P38-protein is known to be expressed in colorectal adenomas (CRA). Expression in low- and high-grade tubular adenomas is decreased when compared to adenocarcinomas and increased with regard to normal mucosa. We aimed to study P38 expression in human CRAs and the relationships to cell proliferation Ki67-protein, stem-phenotype CD133-protein and, to mTOR-protein (AKT pathway). METHODS: The...
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