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Transcriptome Profile of Human Colorectal Adenomas

1 Dec 2007

Abstract excerpt

Colorectal cancers are believed to arise predominantly from adenomas. Although these precancerous lesions have been subjected to extensive clinical, pathologic, and molecular analyses, little is currently known about the global gene expression changes accompanying their formation. To characterize the molecular processes underlying the transformation of normal colonic epithelium, we compared the transcriptomes of...

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PMID: 18171984
DOI: 10.1158/1541-7786.mcr-07-0267

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