Article
Association of erosive hand osteoarthritis with a single nucleotide polymorphism on the gene encoding interleukin-1 beta.
Osteoarthritis and cartilage - 1 Jun 2003
Stern A G, de Carvalho M R C, Buck G A, Adler R A, Rao T P S, Disler D, Moxley G
Abstract excerpt
OBJECTIVE: Certain forms of primary osteoarthritis (OA), particularly those affecting hand joints, have a genetic component. Recent studies have shown suggestive evidence that hand and knee OA are linked with the interleukin-1 (IL-1) region on human chromosome 2q. This study was undertaken to assess the association of primary OA of the hand (hand OA) with IL-1 region markers. METHODS: Sixty-eight US Caucasoid...
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