Article
Allele-specific H3K79 Di- versus trimethylation distinguishes opposite parental alleles at imprinted regions.
Molecular and cellular biology - 1 Jun 2010
Singh Purnima, Han Li, Rivas Guillermo E, Lee Dong-Hoon, Nicholson Thomas B, Larson Garrett P, Chen Taiping, Szabó Piroska E
Abstract excerpt
Imprinted gene expression corresponds to parental allele-specific DNA CpG methylation and chromatin composition. Histone tail covalent modifications have been extensively studied, but it is not known whether modifications in the histone globular domains can also discriminate between the parental alleles. Using multiplex chromatin immunoprecipitation-single nucleotide primer extension (ChIP-SNuPE) assays, we...
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