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Article

CD133 expression in chemo-resistant Ewing sarcoma cells

26 Mar 2010

Abstract excerpt

BACKGROUND: Some human cancers demonstrate cellular hierarchies in which tumor-initiating cancer stem cells generate progeny cells with reduced tumorigenic potential. This cancer stem cell population is proposed to be a source of therapy-resistant and recurrent disease. Ewing sarcoma family tumors (ESFT) are highly aggressive cancers in which drug-resistant, relapsed disease remains a significant clinical...

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PMID: 20346143
DOI: 10.1186/1471-2407-10-116

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