Article
Genetic diversity of the E protein of dengue type 3 virus.
Virology journal - 23 Jul 2009
Amarilla Alberto A, de Almeida Flavia T, Jorge Daniel M, Alfonso Helda L, de Castro-Jorge Luiza A, Nogueira Nadia A, Figueiredo Luiz T, Aquino Victor H
Abstract excerpt
BACKGROUND: Dengue is the most important arbovirus disease in tropical and subtropical countries. The viral envelope (E) protein is responsible for cell receptor binding and is the main target of neutralizing antibodies. The aim of this study was to analyze the diversity of the E protein gene of DENV-3. E protein gene sequences of 20 new viruses isolated in Ribeirao Preto, Brazil, and 427 sequences retrieved from...
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