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Article

Warburg tumours and the mechanisms of mitochondrial tumour suppressor genes. Barking up the right tree?

Current opinion in genetics & development - 1 Jun 2010

Bayley Jean-Pierre, Devilee Peter

Abstract excerpt

The past decade has seen a revival of interest in the metabolic adaptations of tumours, named for their original discoverer, Otto Warburg. Warburg reported a high rate of glycolysis in tumours, and a concurrent defect in mitochondrial respiration. The rediscovery of Warburg's hypothesis coincided with the discovery of mitochondrial tumours suppressor genes that may conform to Warburg's hypothesis. Succinate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20304625
DOI: 10.1016/j.gde.2010.02.008

Genes

IDH1
SDHAF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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