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Article

Rare insights into cancer biology.

Oncogene - 15 May 2014

Adam J, Yang M, Soga T, Pollard P J

Abstract excerpt

Cancer-associated mutations have been identified in the metabolic genes succinate dehydrogenase (SDH), fumarate hydratase (FH) and isocitrate dehydrogenase (IDH), advancing and challenging our understanding of cellular function and disease mechanisms and providing direct links between dysregulated metabolism and cancer. Some striking parallels exist in the cellular consequences of the genetic mutations within...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23812428
DOI: 10.1038/onc.2013.222

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Rare insights into cancer biology.PMID 23812428Read ↗

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FH Variant Pathogenicity Promotes Purine Salvage Pathway Dependence in Kidney CancerSemantic proximity Read ↗

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