Article
Dynamic regulation of Gata1 expression during the maturation of conventional dendritic cells.
Experimental hematology - 1 Jun 2010
Kozma Gergely T, Martelli Fabrizio, Verrucci Maria, Gutiérrez Laura, Migliaccio Giovanni, Sanchez Massimo, Alfani Elena, Philipsen Sjaak, Migliaccio Anna Rita
Abstract excerpt
OBJECTIVES: To identify the regulatory sequences driving Gata1 expression in conventional dendritic cells (cDC). MATERIALS AND METHODS: The number and expression levels of Gata1, Gata1-target genes and hypersensitive site (HS) 2 (the eosinophil-specific enhancer)-driven green fluorescent protein (GFP) reporter of cDCs from mice lacking HS1 (the erythroid/megakaryocytic-specific enhancer, Gata1(low) mutation) and...
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