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Article

Transcription Factors in Eosinophil Development and As Therapeutic Targets

24 Jul 2017

Abstract excerpt

Dynamic gene expression is a major regulatory mechanism that directs hematopoietic cell fate and differentiation, including eosinophil-lineage commitment and eosinophil differentiation. Though GATA-1 is well established as a critical transcription factor for eosinophil development, delineating the transcriptional networks that regulate eosinophil development at homeostasis and in inflammatory states is not...

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PMID: 28791289
DOI: 10.3389/fmed.2017.00115

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