Article
Regulation of YB-1 gene expression by GATA transcription factors.
Biochemical and biophysical research communications - 28 Mar 2003
Yokoyama Hisayuki, Harigae Hideo, Takahashi Shinichiro, Takahashi Satoru, Furuyama Kazumichi, Kaku Mitsuo, Yamamoto Masayuki, Sasaki Takeshi
Abstract excerpt
GATA-1 is a transcription factor essential for erythroid cell development, and knockdown of GATA-1 gene results in maturation arrest and transformation of erythroblasts. To clarify the mechanism that gives rise to this abnormal phenotype, genes that are aberrantly expressed in the spleen of heter...
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