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Article

FLT3 internal tandem duplication and FLT3-D835 mutation in 80 AML patients categorized into cytogenetic risk groups.

Postepy higieny i medycyny doswiadczalnej (Online) - 18 Oct 2010

Mały Ewa, Przyborsk Marta, Nowak Tomasz, Nowak Jerzy, Januszkiewicz Danuta

Abstract excerpt

BACKGROUND: Acute myeloid leukemia (AML) is a clonal disorder characterized by various genetic abnormalities and variable response to treatment. About 50% of patients with AML have no cytogenetic aberrations, presenting normal karyotype, and are categorized in the intermediate risk group. In this group detection of FLT3 mutations move a patient from the intermediate to the adverse risk group. MATERIAL/METHODS:...

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Source

Identifiers

PMID: 20966504

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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