Article
Promotion of cell spreading and migration by vascular endothelial-protein tyrosine phosphatase (VE-PTP) in cooperation with integrins.
Journal of cellular physiology - 1 Jul 2010
Mori Munemasa, Murata Yoji, Kotani Takenori, Kusakari Shinya, Ohnishi Hiroshi, Saito Yasuyuki, Okazawa Hideki, Ishizuka Tamotsu, Mori Masatomo, Matozaki Takashi
Abstract excerpt
Vascular endothelial-protein tyrosine phosphatase (VE-PTP) is a receptor-type protein tyrosine phosphatase with a single catalytic domain in its cytoplasmic region and multiple fibronectin type III-like domains in its extracellular region. VE-PTP is expressed specifically in endothelial cells and is implicated in regulation of angiogenesis. The molecular basis for such regulation by VE-PTP has remained largely...
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