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Article

HPA Axis Genes, and Their Interaction with Childhood Maltreatment, are Related to Cortisol Levels and Stress-Related Phenotypes.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 2017

Gerritsen Lotte, Milaneschi Yuri, Vinkers Christiaan H, van Hemert Albert M, van Velzen Laura, Schmaal Lianne, Penninx Brenda Wjh

Abstract excerpt

Stress responses are controlled by the hypothalamus pituitary adrenal (HPA)-axis and maladaptive stress responses are associated with the onset and maintenance of stress-related disorders such as major depressive disorder (MDD). Genes that play a role in the HPA-axis regulation may likely contribute to the relation between relevant neurobiological substrates and stress-related disorders. Therefore, we performed...

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Source

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Identifiers

PMID: 28589964
DOI: 10.1038/npp.2017.118
PMCID: PMC5645736

Genes

CRH
DST
FKBP5
POMC
PROP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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