[Human chromosome 8p11 (CHRNB3-CHRNA6) region gene polymorphisms and susceptibility to lung cancer in Chinese Han population].

doi:10.3724/sp.j.1005.2011.00886

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[Human chromosome 8p11 (CHRNB3-CHRNA6) region gene polymorphisms and susceptibility to lung cancer in Chinese Han population].

Yi chuan = Hereditas - 1 Aug 2011

Zhang Xiao-Bo, Zhao Zhen-Hong, Chen Hong-Yan, Wang Jiu-Cun, Qian Ji, Yang Ya-Jun, Wei Qing-Yi, Huang Jian, Lu Da-Ru

Abstract excerpt

To investigate the association between chromosome 8p11 (CHRNB3-CHRNA6) polymorphisms and lung cancer susceptibility in Chinese Han population, we genotyped 6 tag SNPs variants of this region among 784 patients with lung cancer and 782 age- and sex-matched cancer-free control participants to screen for any risk-associated SNPs. The results revealed that rs16891561 TT genotype had a protective effect against lung...

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PMID: 21831805
DOI: 10.3724/sp.j.1005.2011.00886

Genes

CHRNA6
CHRNB3

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