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Article

Diminished cardiac fibrosis in heart failure is associated with altered ventricular arrhythmia phenotype.

Journal of cardiovascular electrophysiology - 1 Sept 2010

Massare Jorge, Berry Jeff M, Luo Xiang, Rob Farhana, Johnstone Janet L, Shelton John M, Bassel-Duby Rhonda, Hill Joseph A, Naseem R Haris

Abstract excerpt

OBJECTIVES: We sought to define the role of interstitial fibrosis in the proarrhythmic phenotype of failing ventricular myocardium. BACKGROUND: Multiple cellular events that occur during pathological remodeling of the failing ventricle are implicated in the genesis of ventricular tachycardia (VT), including interstitial fibrosis. Recent studies suggest that ventricular fibrosis is reversible, and current...

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Source

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Identifiers

PMID: 20233273
DOI: 10.1111/j.1540-8167.2010.01736.x
PMCID: PMC3703442

Genes

PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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