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Article

Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog.

Heart rhythm - 1 Nov 2012

Bourgonje Vincent J A, Schoenmakers Marieke, Beekman Jet D M, van der Nagel Roel, Houtman Marien J C, Miedema Lars F, Antoons Gudrun, Sipido Karin, de Windt Leon J, van Veen Toon A B, Vos Marc A

Abstract excerpt

BACKGROUND: The calcium-dependent signaling molecules calcineurin and calcium/calmodulin-dependent protein kinase II (CaMKII) both have been linked to decompensated hypertrophy and arrhythmias. CaMKII is also believed to be involved in acute modulation of ion channels. OBJECTIVE: The purpose of t...

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Source

Identifiers

PMID: 22846339
DOI: 10.1016/j.hrthm.2012.07.023

Genes

HDAC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22846339-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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