Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Involvement of the cerebral cortex in Parkinson disease linked with G2019S LRRK2 mutation without cognitive impairment.

Acta neuropathologica - 1 Aug 2010

Gomez Anna, Ferrer Isidre

Abstract excerpt

Previous studies have shown altered synuclein, increased oxidative stress damage and increased oxidative stress responses in patients with sporadic Parkinson's disease (PD) without cognitive impairment. Yet no information exists about possible molecular alterations in the cerebral cortex in familial PD. The present study shows abnormal alpha-synuclein solubility and aggregation, and aggregated nitrated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Synuclein
Share to Electrophoresis, Gel, Two-Dimensional
Share to Glial Fibrillary Acidic Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Malondialdehyde

Share to Receptor for Advanced Glycation End Products

Share to Receptors, Immunologic

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 20232069
DOI: 10.1007/s00401-010-0669-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Involvement of the cerebral cortex in Parkinson disease linked with G2019S LRRK2 mutation without cognitive impairment.PMID 20232069Read ↗

Clinical and pathological characteristics of LRRK2 G2019S patients with PD.Semantic proximity Read ↗

LRRK2 and Protein Aggregation in Parkinson’s Disease: Insights From Animal ModelsSemantic proximity Read ↗

LRRK2 and neurodegeneration.Semantic proximity Read ↗

Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain.Semantic proximity Read ↗

Widespread Distribution of α-Synuclein Oligomers in <i>LRRK2</i> -related Parkinson’s DiseaseSemantic proximity Read ↗

G2019S-LRRK2 mutation enhances MPTP-linked Parkinsonism in mice.Semantic proximity Read ↗

Alzheimer's disease tau is a prominent pathology in LRRK2 Parkinson's disease.Semantic proximity Read ↗

LRRK2 Quantification in Cerebrospinal Fluid of Patients with Parkinson's Disease and Atypical Parkinsonian Syndromes.Semantic proximity Read ↗

LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: a morphological and quantitative study.Semantic proximity Read ↗

TDP-43 pathology in a patient carrying G2019S LRRK2 mutation and a novel p.Q124E MAPT.Semantic proximity Read ↗

Parkinson's Disease Associated with G2019S LRRK2 Mutations without Lewy Body Pathology.Semantic proximity Read ↗

Proteasomal dysfunction in sporadic Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.