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Article

Parkinson's Disease Associated with G2019S LRRK2 Mutations without Lewy Body Pathology.

Movement disorders clinical practice - 1 Jul 2024

Jackson Lauren M, Woodruff Bryan K, Tremblay Cecilia, Shill Holly A, Beach Thomas G, Serrano Geidy E, Adler Charles H

Abstract excerpt

BACKGROUND: The G2019S leucine-rich repeat kinase 2 (LRRK2) gene mutation is an important and commonly found genetic determinant of Parkinson's disease (PD). The neuropathological findings associated with this mutation have thus far been varied but are most often associated with Lewy body (LB) pathology. OBJECTIVE: Describe a case of clinical Parkinson's disease with levodopa responsiveness found to have LRRK2...

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Identifiers

PMID: 38757351
DOI: 10.1002/mdc3.14068
PMCID: PMC11233835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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