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Article

Inference of the haplotype effect in a matched case-control study using unphased genotype data.

The international journal of biostatistics - 8 May 2008

Sinha Samiran, Gruber Stephen B, Mukherjee Bhramar, Rennert Gad

Abstract excerpt

Typically locus specific genotype data do not contain information regarding the gametic phase of haplotypes, especially when an individual is heterozygous at more than one locus among a large number of linked polymorphic loci. Thus, studying disease-haplotype association using unphased genotype data is essentially a problem of handling a missing covariate in a case-control design. There are several methods for...

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Identifiers

PMID: 20231916
DOI: 10.2202/1557-4679.1079
PMCID: PMC2835450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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