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Article

Conditional likelihood methods for haplotype-based association analysis using matched case-control data.

Biometrics - 1 Dec 2007

Chen Jinbo, Rodriguez Carmen

Abstract excerpt

Genetic epidemiologists routinely assess disease susceptibility in relation to haplotypes, that is, combinations of alleles on a single chromosome. We study statistical methods for inferring haplotype-related disease risk using single nucleotide polymorphism (SNP) genotype data from matched case-control studies, where controls are individually matched to cases on some selected factors. Assuming a logistic...

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Identifiers

PMID: 18078481
DOI: 10.1111/j.1541-0420.2007.00797.x

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