Article
Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor.
Blood - 15 Jul 2010
Flood Veronica H, Gill Joan Cox, Morateck Patricia A, Christopherson Pamela A, Friedman Kenneth D, Haberichter Sandra L, Branchford Brian R, Hoffmann Raymond G, Abshire Thomas C, Di Paola Jorge A, Hoots W Keith, Leissinger Cindy, Lusher Jeanne M, Ragni Margaret V, Shapiro Amy D, Montgomery Robert R
Abstract excerpt
The diagnosis of von Willebrand disease relies on abnormalities in specific tests of von Willebrand factor (VWF), including VWF antigen (VWF:Ag) and VWF ristocetin cofactor activity (VWF:RCo). When examining healthy controls enrolled in the T. S. Zimmerman Program for the Molecular and Clinical Biology of von Willebrand disease, we, like others, found a lower mean VWF:RCo compared with VWF:Ag in African American...
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