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Article

Possible race and gender divergence in association of genetic variations with plasma von Willebrand factor: a study of ARIC and 1000 genome cohorts.

PloS one - 1 Jan 2014

Zhou Zhou, Yu Fuli, Buchanan Ashley, Fu Yuanyuan, Campos Marco, Wu Kenneth K, Chambless Lloyd E, Folsom Aaron R, Boerwinkle Eric, Dong Jing-fei

Abstract excerpt

The synthesis, secretion and clearance of von Willebrand factor (VWF) are regulated by genetic variations in coding and promoter regions of the VWF gene. We have previously identified 19 single nucleotide polymorphisms (SNPs), primarily in introns that are associated with VWF antigen levels in subjects of European descent. In this study, we conducted race by gender analyses to compare the association of VWF SNPs...

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Source

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Identifiers

PMID: 24465435
DOI: 10.1371/journal.pone.0084810
PMCID: PMC3894939

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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