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Article

C1584: effect on von Willebrand factor proteolysis and von Willebrand factor antigen levels.

Acta haematologica - 1 Jan 2009

Davies James Anthony, Collins Peter William, Hathaway Lee Sarah, Bowen Derrick John

Abstract excerpt

The present review provides a clearer picture of the effect of C1584 on the level and properties of von Willebrand factor (VWF). The C1584 variant is associated with decreased VWF levels (especially in combination with blood group O) and VWF function, and with slightly enhanced VWF proteolysis, and there is evidence to support its association with enhanced VWF clearance. These properties help explain the...

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Share to ABO Blood-Group System
Share to ADAM Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Metabolic Clearance Rate

Share to Protein Structure, Quaternary

Share to von Willebrand Diseases

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Source

Identifiers

PMID: 19506354
DOI: 10.1159/000214848

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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