Article
Phosphorylation by Nek1 regulates opening and closing of voltage dependent anion channel 1.
Biochemical and biophysical research communications - 9 Apr 2010
Chen Yumay, Gaczynska Maria, Osmulski Pawel, Polci Rosaria, Riley Daniel J
Abstract excerpt
VDAC1 is a key component of the mitochondrial permeability transition pore. To initiate apoptosis and certain other forms of cell death, mitochondria become permeable such that cytochrome c and other pre-apoptotic molecules resident inside the mitochondria enter the cytosol and activate apoptotic...
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