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Article

A postincision-deficient TFIIH causes replication fork breakage and uncovers alternative Rad51- or Pol32-mediated restart mechanisms.

Molecular cell - 12 Mar 2010

Moriel-Carretero María, Aguilera Andrés

Abstract excerpt

Homologous recombination is a major double-strand break (DSB) repair mechanism that acts during the S and G2 phases. In contrast, nucleotide excision repair (NER) is a major pathway for the repair of DNA bulky adducts that is unrelated to replication. We show that replication can be strongly dist...

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Share to DNA Breaks, Double-Stranded
Share to Dose-Response Relationship, Radiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Rad52 DNA Repair and Recombination Protein

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Source

Identifiers

PMID: 20227372
DOI: 10.1016/j.molcel.2010.02.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20227372-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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