Article
Generation of DNA single-strand displacement by compromised nucleotide excision repair.
The EMBO journal - 29 Aug 2012
Godon Camille, Mourgues Sophie, Nonnekens Julie, Mourcet Amandine, Coin Fréderic, Vermeulen Wim, Mari Pierre-Olivier, Giglia-Mari Giuseppina
Abstract excerpt
Nucleotide excision repair (NER) is a precisely coordinated process essential to avoid DNA damage-induced cellular malfunction and mutagenesis. Here, we investigate the mechanistic details and effects of the NER machinery when it is compromised by a pathologically significant mutation in a subuni...
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