Article
Polymorphisms in the platelet-specific collagen receptor GP6 are associated with risk of nonfatal myocardial infarction in Caucasians.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Aug 2011
Shaffer J R, Kammerer C M, Dorn J, Ferrell R E, Iacoviello L, Trevisan M, Donahue R P
Abstract excerpt
BACKGROUND AND AIMS: Glycoprotein 6 (GP6) is a platelet-specific collagen receptor implicated in the thrombotic pathway to acute myocardial infarction (AMI), but a possible genetic relationship between GP6 and AMI is poorly understood. We tested for the genetic association between AMI and single nucleotide polymorphisms (SNPs) in 24 loci, including GP6. METHODS AND RESULTS: We conducted a case-control study of...
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