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Article

Common genetic variation in the prothrombin gene, hormone therapy, and incident nonfatal myocardial infarction in postmenopausal women.

American journal of epidemiology - 1 Apr 2006

Hindorff Lucia A, Psaty Bruce M, Carlson Christopher S, Heckbert Susan R, Lumley Thomas, Smith Nicholas L, Lemaitre Rozenn N, Rieder Mark J, Nickerson Deborah A, Reiner Alexander P

Abstract excerpt

Genetic variants in coagulation factors are associated with myocardial infarction and may modify the association between hormone therapy and cardiovascular disease risk. This study assessed whether common variation in the prothrombin gene was associated with incident nonfatal myocardial infarction in postmenopausal women and whether this association differed according to current estrogen use. Eight variants...

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PMID: 16467413
DOI: 10.1093/aje/kwj092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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