Article
Genetic alterations at 13q14 may correlate with differences in the biological behavior of prostate cancer between Japanese and Caucasian men.
Urologia internationalis - 1 Jan 2010
Misumi Taku, Yamamoto Yoshiaki, Murakami Tomoyuki, Kawai Yoshihisa, Ito Hideaki, Eguchi Satoshi, Yano Seiji, Nagao Kazuhiro, Hara Takahiko, Sakano Shigeru, Naito Katsusuke, Sasaki Kohsuke, Fuellhase Claudius, Arenas Luis, Fichtner Jan, Matsuyama Hideyasu
Abstract excerpt
The incidence of prostate cancer and the resultant mortality rates in Japanese men are lower compared with the rates for Caucasians; however, the Gleason score at diagnosis is higher in Japanese men compared with Caucasians. Loss of 13q is one of the most common chromosomal alterations in prostate cancer. To elucidate the difference in the rate of loss of 13q between Japanese and Caucasian men, we examined the...
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