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Article

E2F1-deficient NOD/SCID mice are an experimental model for dry mouth.

The journal of medical investigation : JMI - 1 Jan 2009

Satoh Keitaro, Narita Takanori, Matsui-Inohara Hikaru, Ito Tatsuro, Senpuku Hidenobu, Sugiya Hiroshi

Abstract excerpt

Saliva contains a wide variety of secretory proteins, including alpha-amylase, lysozyme, peroxidase, immunoglobulins, and mucins. Hyposecretion of saliva and consequent dry mouth will lead to severe dental caries, periodontal disease, and mucosal infections, resulting in degrade of quality of life. Polyposia development is one of sign usually seen in dry mouth patients. However, little is reported in dry...

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Identifiers

PMID: 20224195
DOI: 10.2152/jmi.56.260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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