Article
Genetic control of leucocyte--endothelial cell interaction in collagen-induced arthritis.
Annals of the rheumatic diseases - 1 Mar 2010
Tu-Rapp Hoang, Pu Liying, Marques Andreia, Kulisch Christoph, Yu Xinhua, Gierer Philip, Ibrahim Saleh M, Vollmar Brigitte
Abstract excerpt
OBJECTIVE: Despite considerable work on defining disease pathways, several aspects of collagen-induced arthritis (CIA) remain poorly defined, in particular those contributing to the initiation phase of the disease. It is thought that in CIA the activation of circulating leucocytes, their interaction with the endothelial lining followed by subsequent transendothelial migration and infiltration into tissue...
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