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Article

TGF‐β signaling is dynamically regulated during the alveolarization of rodent and human lungs

19 Dec 2007

Abstract excerpt

Although transforming growth factor-beta (TGF-beta) signaling negatively regulates branching morphogenesis in early lung development, few studies to date have addressed the role of this family of growth factors during late lung development. We describe here that the expression, tissue localization, and activity of components of the TGF-beta signaling machinery are dynamically regulated during late lung...

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PMID: 18095342
DOI: 10.1002/dvdy.21403

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