DSP1 interacts with bicoid for knirps enhancement.

doi:10.1002/gene.10201

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Article

DSP1 interacts with bicoid for knirps enhancement.

Genesis (New York, N.Y. : 2000) - 1 Jun 2003

Daulny A, Rappailles A, Landemarre L, Locker D, Decoville M

Abstract excerpt

DSP1 is an HMG-box protein which has been implicated in the regulation of homeotic genes in Drosophila melanogaster. Here we report that DSP1 is also involved in the regulation of the kni gap gene. Analysis of the phenotype of a null mutation of dsp1 (dsp1(1)) reveals that the absence of maternal DSP1 results in A4 segmentation defects that are correlated with a diminution of the kni expression domain. Genetic...

Topics

Animals
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
High Mobility Group Proteins
Homeodomain Proteins
Mutation
Protein Binding
Regulatory Sequences, Nucleic Acid
Repressor Proteins
Trans-Activators

Source

Open in PubMed

Identifiers

PMID: 12820172
DOI: 10.1002/gene.10201

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