Article
The impact of the apolipoprotein E polymorphism on the lipoprotein profile in insulin-dependent diabetes: the Pittsburgh Epidemiology of Diabetes Complications Study IX.
Metabolism: clinical and experimental - 1 Apr 1992
Eichner J E, Ferrell R E, Kamboh M I, Kuller L H, Becker D J, Drash A L, Stein E A, Orchard T J
Abstract excerpt
The apolipoprotein (apo) E polymorphism has been related to differences in lipoprotein metabolism and lipid/lipoprotein concentrations in a number of studies. Whether these associations are seen in insulin-dependent diabetes mellitus (IDDM), which itself affects many of the same aspects of lipoprotein metabolism as does the apo E polymorphism, is unknown. The present study is an investigation into the influence...
Topics
- Adult
- Alleles
- Apolipoproteins E
- Diabetes Mellitus, Type 1
- Female
- Gene Frequency
- Humans
- Lipoproteins
- Male
- Middle Aged
- Phenotype