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Article

Wild-type BRCA1, but not mutated BRCA1, regulates the expression of the nuclear form of beta-catenin.

Molecular cancer research : MCR - 1 Mar 2010

Li Huchun, Sekine Masayuki, Tung Nadine, Avraham Hava Karsenty

Abstract excerpt

BRCA1 is an essential caretaker protein in the surveillance of DNA damage, is mutated in approximately 50% of all hereditary breast cancer cases, and its expression is frequently decreased in sporadic breast cancer. beta-Catenin is a multifunctional protein that forms adhesion complex with E-cadh...

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Identifiers

PMID: 20215423
DOI: 10.1158/1541-7786.MCR-09-0403
PMCID: PMC2867250

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20215423-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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