Article
Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand.
Circulation research - 16 Apr 2010
Kim Il-Man, Wolf Matthew J, Rockman Howard A
Abstract excerpt
RATIONALE: Drosophila has been recognized as a model to study human cardiac diseases. OBJECTIVE: Despite these findings, and the wealth of tools that are available to the fly community, forward genetic screens for adult heart phenotypes have been rarely performed because of the difficulty in accurately measuring cardiac function in adult Drosophila. METHODS AND RESULTS: Using optical coherence tomography to...
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