Article
SPARC-Dependent Cardiomyopathy in Drosophila.
Circulation. Cardiovascular genetics - 1 Apr 2016
Hartley Paul S, Motamedchaboki Khatereh, Bodmer Rolf, Ocorr Karen
Abstract excerpt
BACKGROUND: The Drosophila heart is an important model for studying the genetics underpinning mammalian cardiac function. The system comprises contractile cardiomyocytes, adjacent to which are pairs of highly endocytic pericardial nephrocytes that modulate cardiac function by uncharacterized mechanisms. Identifying these mechanisms and the molecules involved is important because they may be relevant to human...
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