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Article

Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype.

Aging cell - 1 Mar 2008

Taghli-Lamallem Ouarda, Akasaka Takeshi, Hogg Grant, Nudel Uri, Yaffe David, Chamberlain Jeffrey S, Ocorr Karen, Bodmer Rolf

Abstract excerpt

A number of studies have been conducted recently on the model organism Drosophila to determine the function of genes involved in human disease, including those implicated in neurological disorders, cancer and metabolic and cardiovascular diseases. The simple structure and physiology of the Drosophila heart tube together with the available genetics provide a suitable in vivo assay system for studying cardiac gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18221418
DOI: 10.1111/j.1474-9726.2008.00367.x
PMCID: PMC2840698

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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