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Article

Drosophila as a model for the identification of genes causing adult human heart disease.

Proceedings of the National Academy of Sciences of the United States of America - 31 Jan 2006

Wolf Matthew J, Amrein Hubert, Izatt Joseph A, Choma Michael A, Reedy Mary C, Rockman Howard A

Abstract excerpt

Drosophila melanogaster genetics provides the advantage of molecularly defined P-element insertions and deletions that span the entire genome. Although Drosophila has been extensively used as a model system to study heart development, it has not been used to dissect the genetics of adult human heart disease because of an inability to phenotype the adult fly heart in vivo. Here we report the development of a...

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Identifiers

PMID: 16432241
DOI: 10.1073/pnas.0507359103
PMCID: PMC1360529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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